A COMPREHENSIVE REVIEW OF “NANOEMULSION”

Monika, Kavita Kumari* and Sanjiv Duggal

Nanoemulsions are form of novel drug delivery system (NDDS) which is used to increase the solubility and stability which results in the increase of bioavailability of medications that are not highly water soluble. Nanoemulsions are submicron sized emulsions which work as medication carriers for enhancing the delivery of therapeutic substances. Droplet size of nanoemulsion ranges from 20 to 200nm. These are thermodynamically stable isotropic systems made up of two immiscible liquids which are mixed up with surfactants and co-surfactant (emulsifying agents) to reduces the surface and interfacial tension. Nanoemulsions are prepared by using two methods these are high energy methods and low energy methods. A variety of analytical methods are described to evaluate droplet size, stability, and interaction with biological systems in the context of nanoemulsion assessment. It includes physical and chemical instabilities along with thermodynamic stability. Nanoemulsions have potential use in cosmetics, diagnostics, medicinal treatments, and biotechnology. Commercial products, marketed products and patented nanoemulsion are also discussed.