THERAPEUTIC POTENTIAL AND PHARMACOLOGICAL INSIGHTS OF CBD GUMMIES: A COMPREHENSIVE REVIEW

Geddada Maheswari*, Meka Pooja, Chodipilli Revanth Durga, Peddireddy Lokesh Babu, Khandavalli Sheba, Boddani Sunil

Cannabidiol (CBD), a non-psychoactive constituent of Cannabis sativa, has gained remarkable scientific and therapeutic attention in recent years. Among its various formulations, CBD gummies have emerged as a popular oral dosage form due to their ease of administration, palatability, and patient compliance. This review aims to provide a comprehensive overview of the pharmacology, mechanism of action, therapeutic potential, and safety profile of CBD gummies. The article highlights the pharmacokinetic behavior of CBD, its interaction with the endocannabinoid system, and its influence on CB1 and CB2 receptors. Furthermore, evidence from preclinical and clinical studies is discussed to emphasize the role of CBD in managing anxiety, epilepsy, chronic pain, and inflammation. The review also explores the formulation aspects, quality control parameters, and legal regulations, particularly within the Indian context. Despite promising outcomes, challenges such as standardization, dosage optimization, and regulatory restrictions remain significant hurdles to clinical application. This paper underscores the need for further research to establish CBD gummies as a scientifically validated, safe, and effective therapeutic option in modern pharmaceutics.