ABSTRACT
CYTOTOXIC EFFICIENCY AND ANTIPROLIFERATIVE ACTIVITY OF THE ISOLATED COMPOUND AND ATROPINE FROM DATURA STRAMONIUM SEEDS AGAINST HIGHLY METASTATIC CERVICAL CANCER HELA CELL
Zoya Amreen*, Shriyansha, Shama Parveen, Ana Ahtsham, Monisha Banerjee, Meenakshi Singh
The main aim of the present research study was to evaluate the antiproliferative activity against the highly metastatic cervical cancer of the compound isolated from the acetone extract of the seeds and atropine of Datura stramonium. Using MTT assay the cytotoxic assay was calculated. Significant morphological changes were observed in a dose dependent manner when treated with acetone extracts of D. stramonium. For further investigation of the active principles this recent work gives a push for the much needed treatment against the metastatic cervical cancer.
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