NEURO PROTECTIVE POTENTIAL OF CINNAMON IN THE MANAGEMENT OF ALZHEIMER’ SDISEASE

Dr. N. Charitha, K. Mabu Chanu, K. Varalakshmi, K. Sripriya, K. Afifa, K. Pavithra

Alzheimer’s disease is a progressive neurodegenerative disorder characterized by cognitive decline, stress, and neuronal damage. The present study aimed to evaluate the neuroprotective potential of cinnamon through in vitro antioxidant activity. Cinnamon powder was extracted using methanol by maceration, followed by photochemical screening. The antioxidant activity was assessed using lipid peroxidation inhibition assay and compared with ascorbic acid as standard. The extract demonstrated significant concentration-dependent anti oxidant activity, with marked reduction in oxidative stress markers. The findings suggest that cinnamon pos- sesses promising neuroprotective properties due to its antioxidant and anti-inflammatory phy- toconstituents. Further in vivo and clinical studies are required to establish its therapeutic role in Alzheimer’s disease.