World Journal of Pharmaceutical
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ISSN: 2583-6579


Impact Factor: 6.916

ABSTRACT

FORMULATION AND EVALUATION OF HERBAL ANTI-WRIKLE MOISTURIZER USING SHATA DHAUTA GHRITA BASE

Asadullah*, Rahul Sharma, Srishti Saini, Dinesh Upadhyay, Subhranshu Panda

Aging is an inevitable biological process characterized by progressive structural and functional changes in the skin, leading to the formation of wrinkles, fine lines, and loss of elasticity. The present study was aimed at the formulation and evaluation of a herbal anti-wrinkle moisturizing cream using Shata Dhauta Ghrita (SDG) as a base, incorporating natural ingredients with known antioxidant, emollient, and skin-rejuvenating properties. SDG was prepared by the traditional method of washing cow ghee 100 times, resulting in a soft, cream-like base suitable for topical application. The herbal cream was formulated using ingredients such as almond oil, chironji oil, coconut oil, aloe vera gel, glycerin, vitamin E, beeswax, and borax through an emulsification technique. The prepared formulation was evaluated for various physicochemical and microbiological parameters including organoleptic properties, homogeneity, pH, spreadability, viscosity, washability, microbial load, and skin irritation test. The pH of the formulation was found to be in the range of 5.5–6.5, indicating compatibility with skin. The viscosity (≈21,000 cps) and spreadability were within the acceptable range, ensuring ease of application. The formulation showed good homogeneity, was easily washable, and exhibited no signs of irritation during the patch test. Microbial studies confirmed that the product was within acceptable limits for topical use. The presence of natural antioxidants and moisturizing agents in the formulation contributes to hydration, protection against oxidative stress, and improvement in skin texture. Overall, the developed herbal cream demonstrated satisfactory stability and performance, suggesting its potential as a safe and effective anti-wrinkle and moisturizing formulation for maintaining healthy and youthful skin.

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