World Journal of Pharmaceutical
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ISSN: 2583-6579


Impact Factor: 5.111

ABSTRACT

NEUROMYELITIS OPTICA SPECTRUM DISORDER: A CASE REPORT

Dr. Nimmy Davis*

Neuromyelitis optica spectrum disorder (NMOSD), formerly known as neuromyelitis optica (NMO) or Devic’s syndrome or Devic’s disease, was initially considered as part of multiple sclerosis (MS) because the symptoms were considered overlapping. But now, it is known that the pathophysiology of these two diseases is different.[2] Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune disease that causes severe demyelination, especially in the optic nerve and spinal cord with typical clinical manifestations of acute optic neuritis and transverse myelitis. The symptoms can occur simultaneously or separated by a variable period. NMOSD is associated with serum aquaporin antibodies 4 immunoglobulin G (AQP4-IgG).

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