ABSTRACT
DERMAL DRUG DELIVERY THROUGH NANOCARRIERS
Vigneshwaran LV*, Thasneem Abdullakunhi, Fathimath Irfana BM, Thushara PV, V. Sebastin, Ajith Babu TK
Nanocarriers have been explored for delivering drugs and other bioactive molecules for well over 35years. Since the introduction of a nanoliposomal delivery system for the cancer drug doxorubicin, several products have been approved worldwide. The majority of these products focus on cancer chemotherapy, and utilize the size advantage of nanocarriers to obtain a favourable distribution of the drug carrier in the human body. In general, such carriers do not sustain drug release over more than a few days at best. A variety of nanocarriers have been studied, and their advantages and shortcomings are highlighted. The achievement of sustained release of bioactive molecules opens new doors in nanotherapeutics.
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