THE CYTOTOXIC EFFECT OF RETINOID AND RETINOL ON PREGNANT WOMEN

Alaa Abduljabbar Abdulrazzaq, Farah T.O. Al-Jumaili* and Noor A. Oohayyed

Retinol is a subtype of retinoid that is derived from Vitamin A. Unlike prescription retinoids, Over-the-counter retinol is available as a component of skin care products such as lotions, gels, serums, and creams. Retinol may boost the synthesis of collagen and elastin in the dermis, the skin's innermost layer, contributing to its pro-aging and anti-acne properties. The production of more collagen may smooth out wrinkles and fine lines in older skin. In addition to treating blemishes, retinol exfoliates the skin's surface by eliminating dirt, germs, and dead skin cells. Vitamin A, also referred to as retinol is an essential vitamin for daily human function that regulates the cellular growth of epithelial tissue. According to research too much vitamin A can affect how embryos develop and lead to teratogenesis or the development of birth defects in an embryo. Excessive vitamin A and retinoid use during pregnancy often results in fetuses with defects of the face, limbs, eyes, skull, and central nervous systems.Furthermore, retinoids, which are vitamin A derivatives, are frequently prescribed by medical professionals to treat a variety of skin disorders as well as carcinomas, the most prevalent type of cancer in humans.