EXPLORING THE POTENCY OF NOVEL HERBAL DRUG DELIVERY SYSTEMS: A COMPREHENSIVE REVIEW ON ANTIBACTERIAL STUDIES

K. Kavitha* and R. Manivannan

In a scenario of the ineffectiveness of the current drugs against antibiotic-resistant pathogens, the herbal extracts can serve as an alternative remedy. Phyllanthus emblica (gooseberry) leaf extract to synthesize Boron-doped zinc oxide nanosheets (B-doped ZnO-NSs) is deliberated in this article. B doped ZnO-NSs were tested against both gram-positive and gram negative bacterial strains including Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumonia, and Escherichia coli. Against gram-negative bacterium (K.pneumonia and E.coli), B-doped ZnO displays enhanced antibacterial activity with 26 and 24 mm of inhibition zone, respectively. In this study, we report low cost, green synthesis of AgNPs using fresh fruit extract of Phyllanthus emblica. Copper oxide nanoparticles (CuONPs) have emerged as potential antibacterial agents. In this study, we aimed to synthesize CuONPs using Terminalia chebula (T. chebula) dried fruit extract and evaluate their antibacterial activity against specific wound pathogen. In the current research, an aqueous extract of Terminalia chebula fruit was used to produce silver nanoparticles (AgNPs) in a sustainable manner. UV-visible spectrophotometry, transmission electron microscopy (TEM), and scanning electron microscopy (SEM) were used to characterize the synthesized nanoparticles.Terminalia bellerica (TB) dry fruit parts mediated gold nanoparticles were synthesized using the aqueous extracts. The green synthesized gold nanoparticles show vibrant colours. The clinical species such as Acinetobacter pneumonia, Bacillus subtilis, and Enterococcus faecalis which cause common infections. The TB fruit part extracts, as well as TB fruit parts mediated gold nanoparticles were capable enough to destroy clinical pathogens.