World Journal of Pharmaceutical
Science and Research

An International Peer Reviewed Journal for Science & Pharmacy Professional


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ISSN: 2583-6579


Impact Factor: 5.111

ABSTRACT

A REVIEW ON THE THERAPEUTIC POTENTIAL OF GENE THERAPY IN NEUROLOGICAL DISORDERS

Dr. Swapna Moparthi*, S. Priyadharshini, Dr. Sowjanya Kondru, Dr. Srinivasarao Varagani, Dhruvi Pandit, Mohammed Abdul Qader, Morziul Haque, Shaikh Mohammed Taher, Kohale Dhiraj Arvind, Gopalkumar Sunilkumar Singh

Gene therapy is a novel way to treating neurological illnesses, potentially curing some of the most difficult and incurable conditions at this time. This review examines the therapeutic potential of gene therapy for a range of neurological illnesses, with an emphasis on the mechanisms underlying these effects, such as cell-based therapies, gene silencing, gene editing, gene insertion, and gene control. Gene therapy offers intriguing pathways to address the underlying causes of neurological illnesses by repairing genetic defects, lowering toxic protein levels, improving neuroprotection, restoring gene function, and offering long-term solutions. The review focuses on important developments in tailored treatment plans, gene delivery techniques, and ongoing research initiatives that are influencing the direction of gene therapy. A thorough discussion of the therapeutic effects of gene therapy is provided, with an emphasis on how it may change treatment paradigms and enhance patient outcomes for diseases like spinal muscular atrophy, Huntington's disease, ALS, Parkinson's disease, and other neurological disorders.

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