DEVELOPMENT OF SOLID ORAL DOSAGE FORM CONTAINING OSELTAMIVIR FOR USE IN THE TREATMENT OF INFLUENZA ILLNESS FOR ALL PATIENT GROUPS

Canberk Yılmaz*, Cuneyt Toprak, Gokay Gun and Erdınc Babuc

Oseltamivir is administered orally for the treatment and prevention of acute, uncomplicated seasonal influenza infections. The white used is a neuraminidase inhibitor available by prescription. Although there are 3 different types (A, B, C) Oseltamivir shows activity against A and B influenza viruses. The main purpose of this study is to develop a generic product that can be used by patient populations of all ages in the treatment and prevention of seasonal flu infections, which have been very common in recent years. After various trial productions, the designed unit formula was implemented by ensuring homogeneity with the dry mix geometric dilution production method due to its low dose of preservative (Sodium Benzoate). The suitability of the study was evaluated by taking into account the physical and chemical analysis features in the European Pharmacopoeia standards.