World Journal of Pharmaceutical
Science and Research

An International Peer Reviewed Journal for Science & Pharmacy Professional


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ISSN: 2583-6579


Impact Factor: 5.111

ABSTRACT

FORMULATION AND EVALUATION OF SPIRULINA IN HERBAL MOISTURIZING CREAM WITH ANTI MICROBIAL ACTIVITY

N. Jayaramakani*, K. Saifullaha, S. Baladhandapani, L. Kumaraguru, K. Yuvaraj and R. Ranjith

Spirulina, a nutrient-rich blue-green algae, is incorporated as the active ingredient in this formulation due to its high content of vitamins, minerals, and antioxidants, all of which are beneficial for skin health. The formulation includes a carefully selected combination of emollients, humectants, emulsifiers, and preservatives to create a stable and effective cream. Key ingredients include shea butter, coconut oil, glycerin, emulsifying wax, and aloe vera gel. The formulation process involves heating and combining the oil and water phases, followed by cooling and the addition of spirulina and other heat-sensitive components. The resulting cream is then evaluated for its physicochemical properties, such as appearance, pH, viscosity, and spreadability. Stability tests, including accelerated stability testing at various temperatures and freeze-thaw cycles, are conducted to ensure the product’s durability. The moisturizing efficacy of the cream is measured through in vivo testing to determine its ability to enhance skin hydration. The cream may also help reduce skin sensitivity, improve skin tone and texture, and conceal imperfections. Spirulina is rich in bioactive compounds, including phycocyanin, chlorophyll, proteins, vitamins (B1, B2, B3, B6, B9, C, E), minerals (iron, magnesium, calcium, potassium), and essential fatty acids. These components contribute to its antioxidant, anti-inflammatory, and immune-boosting properties. Spirulina works by providing essential nutrients, reducing oxidative stress, enhancing immune function, and supporting overall health. Herbal medications or extracts are commonly used in topical formulations and cosmetics. For example, Arctium lappa L. (Asteraceae) has been used to treat inflammatory conditions and various skin issues, making it a suitable herbal product for healing dry skin. The cream contains several natural ingredients, including liquid paraffin, vitamin E, jasmine oil, Aloe barbadensis (aloe vera leaves), Azadirachta indica (neem), beeswax, and rose oil. The selection of ingredients is based on their therapeutic properties and their ability to enhance the cream’s effectiveness. Spirulina, known as a “superfood” due to its nutrient density, is high in protein, iron, antioxidants, and omega-3 and omega-6 fatty acids, which support heart health, boost energy, reduce inflammation, and improve overall well-being. Spirulina is commonly consumed as a supplement in pill or powder form and can also be added to smoothies, salads, or other recipes. The antioxidant and anti-inflammatory components of the herbal cream formulation help reduce oxidative stress and inflammation. Additionally, its high vitamin E content hydrates and nourishes the skin, preventing it from drying out.

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