PARAMETRIC COMPARISON OF DIABETIC AND NON-DIABETIC CONDITION IN CORONARY ARTERY DISEASE PATIENTS UNDERGOING PCI

K. Madhumitha, Dr. Gokila Shanmuganathan* and Dr. Deepa C. Philip

Background: Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The presence of Type 2 diabetes mellitus (T2DM) is associated with severe and diffuse coronary artery disease. In addition, it is also associated with inferior outcomes following coronary revascularization compared to patients without diabetes mellitus. Method: Patients with stable coronary artery disease undergoing percutaneous coronary intervention (PCI) in the presence of type 2 diabetes mellitus were selected for the study and were grouped into two categories: Group 1 (non-DM) and Group 2 (DM). Various parameters like baseline and clinical characteristics, lab investigations, and patient history were studied and noted. Result: Among 344 CAD patients, it was found that 42.15% were non-diabetic patients and 57.84% of them were diabetic patients. Abnormalities were seen in parameters like BMI, triglyceride, HbA1C, cardiac markers, and hemoglobin. Conclusion: The patients with diabetes may have abnormal parametric values that have an adverse effect on outcome compared to non-diabetic patients. Finally, diabetes is considered a major comorbidity, which leads to worse conditions in CAD patients following coronary revascularization.