DEVELOP AND VALIDATE A SIMPLE, ACCURATE, PRECISE AND A ROBUST HPLC METHOD FOR THE QUANTITATIVE ANALYSIS OF DEFERASIROX IN RAW MATERIAL

Gona Lakshmaiah*, Kaviyarasan M., Kotha Srinivasulu, Suresh Kumar S., Avinash Veeraragan, Amritha J.

Role of pharmaceutical analysis in drug development

Pharmaceutical analysis can be simply defined as analysis of a pharmaceutical compound or drug. Traditionally, pharmaceutical analysis referred to the chemical analysis of drug molecules. However, over the years, modern pharmaceutical analysis has evolved beyond this to encompass combination techniques, high-throughput technologies, chemometrics, microdosing studies, miniaturization and nanotechnology. These analytical advances are now being employed in all stages of drug discovery. With new, improved and evolving technologies, as well as new applications for existing technology, the search for new drugs for the prevention and treatment of human diseases continues. These analyses are needed in a variety of situations that range from an assay of the new chemical entity (NCE) in the presence of related compounds including optical isomers to complex determination of trace or ultratrace level of various related or transformation products.