A CASE-CONTROL STUDY: ASSOCIATION BETWEEN IMMUNIZATIONS AND SEVERE PNEUMONIA IN TERTIARY CARE FACILITY

Zareen Naz*, Faiza Siddiqui and Faiz Ahmed Siddiqui

Objective: To determine association of immunization for severe pneumonia among new born children aged 2-24 months admitted in tertiary care hospital. Study Design: Case-control Study. Place and Duration: Pediatric Ward, Dr Ziauddin University Hospital, North Nazimabad, Karachi. Methodology: Divided into 2 groups contain 144 patients in each group. Identified through non-probability consecutive sampling. Sample size was calculated using WHO sample size calculator and power of test was kept at 80%, P1= 7.8% and P2=1%. Data was analyzed through SPSS version 19 and p-value < 0.05 considered as significant. Association between study variables and severe pneumonia was computed using Chi Square Test. Results: Group A (67 males and 77 females) mean age was 13.00±6.40 months and group B (78 males, 66 females) mean age was 12.83±6.90 months. . In group-A 49.3% were immunized and 72.9% in group-B. 27.1% reported with low birth weight in group-A and 30.6% in group-B. Conclusion: The studied risk factors more prevalent in patients with severe pneumonia rather than controls and significantly associated with severe pneumonia. Immunization was significantly associated with severe pneumonia.