World Journal of Pharmaceutical
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ISSN: 2583-6579


Impact Factor: 5.111

ABSTRACT

A STUDY OF CHANGES IN THE LIPID PROFILE AND LEVELS OF C-REACTIVE PROTEIN DURING PREGNANCY AMONG SOME WOMEN IN AL-NAJAF GOVERNORATE, IRAQ

Zainab Salah Abdul Jabar, Maysoon Khudair AL Hadrawi*, Raja Jawad Mohamed, Sarah Hasan Kadhum AL-Huchaimi

Background: Pregnancy increases metabolic fuel demands for fetal growth and development. It has been estimated that the total energy cost of gestation is approximately 83000 kcal. Also, the energy usage is change and lipid accumulation across pregnancy stages. Aim: To study the changes in the lipid profile and CRP levels among pregnant women in AL Najaf governorate during all pregnancy trimesters. Methods: The current study included 60 pregnant women with different stages of pregnancy, ranging from 6-40 weeks, enjoying a good pregnancy, and their ages ranged between 17-35 years, attending some primary health care centers for motherhood and childhood in AL Najaf, and after obtaining the verbal consent of the women, 5 ml of blood was drawn and placed in Gel tube to prepare the serum needed to measure the level of lipids and C Reactive protein. Results: Our current study, which included 60 women at different stages of pregnancy, recorded a significant change in the level of active protein C at all stages of pregnancy, evidence of a significant effect of pregnancy on this protein compared to the control group. The current study also showed that pregnancy causes significant changes in the levels of lipids (HDL, LDL, Cholesterol, and VLDL), knowing that the results were analyzed based on the SPSS program version 2022, where the effect is considered significant when (p<0.05). Conclusion: This study concluded that pregnancy in women affects CRP levels and levels of lipids in blood.

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