A REVIEW MUCOADHESIVE BUCCAL PATCHES

Sonal Jadhav*, Isha Kanoj, Yashpal M. More

The buccal administration rote is a highly appealing option for delivering drugs systemically. Buccal drug administration enables direct entry into the systemic circulation via the internal jugular vein, bypassing hepatic first-pass metabolism and resulting in enhanced bioavailability. The placement of the product occurs between the upper gingiva (gums) and cheek in order to address both local and systemic conditions. This particular drug delivery approach in deemed advantageous in enhancing the bioavailability of medications. Buccal bio adhesive films offer unique advantages compared to conventional dosage forms in the treatment of various diseases by delivering topical drug at a controlled and gradual place within the oral cavity. This review paper covering various aspects such as the oral mucosa, formulation, mechanism of muco adhesion, active ingredient delivers through buccal route, factors affecting on buccal patches formulation. Furthermore, it also discusses future prospective of buccal patches in drug delivery system.