EFFECT OF SODIUM SULFATE ON HAEMATOLOGICAL PARAMETERS IN MUS MUSCULUS AND ITS AMELIORATION BY AZADIRACHTA INDICA EXTRACT

D. N. Choudhary, Deepak Kumar* and Satya Shandilya

Sulfur compounds are wildly distributed in nature in the form of Sulfates and Sulfites as prominent compound, inter the natural environment through the Sulfure cycle and significantly influencing the human health and hygiene. The present investigation was conducted to evaluate the effect of Sodium sulfate solution in Albino mice and its amelioration by leaf extract of Azadirachta indica. For this investigation 24 Albino mice (Mus musculus) were used. They were divided equally into three groups: A control group and two experimental groups. The control group received a normal diet along with distilled water. First experimental group (8 mice) was orally feed with 1% Sodium sulfate solution (0.5 ml/mice/day) for 28 days, while the second experimental group received both Sodium sulfate (1%) and freshly prepared (2%) aqueous extract of A. Indica (0.5 ml/mice/day) for the same period i.e. 28 days and was maintained on a normal diet with distilled water, similar to control group. Certain haematological parameters including RBC, WBC and Haemoglobin concentration in all the three groups (control and experimental) were estimated after the treatment of 28 days. The above mention parameters were found significantly decreased in case of mice of second group treated with Sodium sulfate solution only. Whereas in the third group of mice treated with both Sodium sulfate as well as the aqueous leaf extract of A. indica showed an increasing trend. The results clearly revealed that the aqueous leaf extract of A. indica could treated mice.