FORMULATION AND EVALUATION OF DUSTING POWDER BY USING CLOTRIMAZOLE

B. Bhumika*, K. Kalyani, K. Jessi Kumari, D. Roja Devi, G. V. R. Naga Bala, Dr. Pisipati Aparna

The objective of this study is to prepare and evaluate clotrimazole dusting powder for its physical characteristics and anti-fungal efficacy. Clotrimazole dusting powder is prepared using clotrimazole, talc, and Salicylic acid, Benzoic acid and menthol. In the present study dusting powder was formulated. The dusting powder is prepared by mixing all the ingredients in an ascending order (Geometric mixing) in mortar pestle for uniform mixing of all ingredients. The prepared dusting powder is then evaluated for various parameters such as colour, odour, appearance (physical characteristics), particle size, bulk density, tapped density and flowability. The results showed that the prepared clotrimazole dusting powder has uniform particle size, good flowability, and suitable bulk density. The powder exhibited significant antimicrobial activity against microorganisms. This study demonstrates the potential of clotrimazole dusting powders as a topical formulation for the treatment of fungal infections is sufficed.