HPV AND CERVICAL CANCER: INSIGHTS INTO PREVENTION, DIAGNOSIS, AND TREATMENT

P. Naina Varshini*, MD. Amatul Haq Kubra, K. Kavyasri

Background: This review examines the potential impact of HPV-16/18 vaccination on age-specific cervical cancer incidence in India. It considers conflicting risks, decreasing immunity, and vaccine coverage and efficacy. The study aims to understand the heterogeneity of vaccine responses, type-specific effects on other HPV types, and the duration of vaccination effects. Objective: The main objective of this review is to learn more about human papillomavirus-related cervical cancer by investigating its basic causes, diagnosis, therapy, prevention and analyzing women’s across worldwide. Methods: The review, spanning 2013-2024, analyzed 14 articles published in electronic health sciences databases, specifically focusing on "India," "understanding," and "cervical cancer assessment." Discussion: The study found that 58.26% of women were aware of cervical cancer, with early sexual activity and marriage increasing the risk. Symptoms included intermenstrual bleeding and foul-smelling discharge. HPV infection significantly influenced cervical malignancies. Lack of knowledge in rural and urban areas suggests the need for programs to increase awareness. Conclusion: Every year, over 1.5 million Indian women receive cervical precancer therapy, with cervix screening for HPV. Adolescent HPV vaccination prevents over 90% of cervical malignancies and precancers.