INTRACOCHLEAR DRUG DELIVERY SYSTEM: CURRENT STATUS AND FUTURE PROSPECTS

Manisha Lavate*, Sujit Karpe, Ritesh Shinde, Pranavraj Bhosale and Akshay Shrimal

Novel treatment methods for millions of patients are being made possible by developments in molecular biology and the fundamental knowledge of the mechanisms behind sensorineural hearing loss and other inner ear disorders. New technologies will be needed to deliver these molecules safely and effectively, though, as the cochlea is a particularly difficult target for pharmacological therapy. New delivery methods based on microfluidic technology are demonstrating potential as a direct intracochlear delivery method. In the end, these devices could be used to distribute regenerative chemicals over a prolonged period of time to help patients with a variety of auditory illnesses regain their hearing. This article's goal is to give a succinct overview of intracochlear medication delivery methods that are presently being developed and may eventually be used in conjunction with newly discovered therapeutic chemicals to treat inner ear disorders. This study focuses on the latest improvements in intratympanic drug delivery; methods that use new biomaterials and other recent advancements are also included.There is a new chance to treat inner ear illnesses better thanks to these inner ear medicine delivery devices.