World Journal of Pharmaceutical
Science and Research

A Global Platform for Open Access, Peer-Reviewed, and Indexed Research in the
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ISSN: 2583-6579


Impact Factor: 5.111

ABSTRACT

FORMULATIONS AND EVALUATION OF EFFERVESCENT MOUTHWASH TABLET

*Shital Arkhade, Ghuge Gayatri, Aher Bhagyashri, Prof. Radhika Kotame and Tejaswini Pawar

The objective of this research was to identify and evaluate dental caries, which result from bacterial presence in the biofilm (dental plaque) on tooth surfaces, leading to localized degradation of hard tissues primarily due to acid production. These degradations are commonly referred to as dental caries. To address the limitations of commercially available liquid mouthwashes that contain artificial active ingredients such as tooth staining, high alcohol content, unpleasant flavors, dry mouth, and stability concerns—a herbal effervescent mouthwash tablet was formulated using menthol and zinc oxide, both of which possess antimicrobial, antibacterial, antiplaque, and anti-inflammatory properties. This study emphasizes the formulation process and examines the effects of the natural extract on adherence, biofilm formation, and cellular substrate hydrolysis. The bacterial strains utilized in this research include Staphylococcus aureus, Bacillus pumilus, Bacillus subtilis, Acinetobacter baumannii, Micrococcus luteus, and Pseudomonas aeruginosa.

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