A RESEARCH ON FORMULATION AND EVALUATION OF CRANBERRY SEED EXTRACT FOR THE TREATMENT OF DERMATITIS

Shiv Shankar Sharma, Abhishek Bhardwaj*, Krati, Dr. Esha Vatsa, Dr. Amandeep Singh

The formulation and evaluation of cranberry seed extract for the treatment of dermatitis were investigated to explore its therapeutic potential as a natural remedy. Cranberry seeds, rich in bioactive compounds such as antioxidants, polyphenols, and essential fatty acids, were extracted using a standardized method to preserve their active constituents. The extract was incorporated into topical formulations, including creams and gels, aimed at treating dermatitis, a chronic skin condition characterized by inflammation, itching, and irritation. Various parameters, including physical appearance, pH, viscosity, and spreadability, were evaluated to ensure the quality and stability of the formulations. In-vitro assays were performed to assess the anti-inflammatory, antioxidant, and antimicrobial properties of the cranberry seed extract. Additionally, clinical trials were conducted to evaluate the efficacy of the formulation in patients with mild to moderate dermatitis. Results indicated that the cranberry seed extract exhibited significant anti-inflammatory effects, improved skin hydration, and reduced symptoms of dermatitis, such as redness and itching. The study concludes that cranberry seed extract can be a promising natural ingredient in the formulation of effective topical treatments for dermatitis, with minimal side effects. Further research is recommended to optimize the formulation and determine long-term efficacy.