World Journal of Pharmaceutical
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ISSN: 2583-6579


Impact Factor: 5.111

ABSTRACT

RENAL CALCULI DISSOLVING PLANTS; A CONSISE REVIEW

Pranjal V. Vasav and Madhuri S. Nalawade*

The formation of renal calculi, also known as urolithiasis, is a multifaceted process that arises from a series of physicochemical events. These events include calcium calculi, struvite calculi, uric acid, and cysteine calculi, which are growth, aggregation, and retention within the renal system. Epidemiological studies indicate that calcium oxalate is the most common mineral found in the majority of renal calculi. Epidemiology has significantly enhanced our comprehension and management of renal calculi. The formation of renal calculi, also known as urolithiasis, is a multifaceted process that arises from a series of physicochemical events. These events include calcium calculi, struvite calculi, uric acid, and cysteine calculi, which are growth, aggregation, and retention within the renal system. Epidemiological studies indicate that calcium oxalate is the most common mineral found in the majority of renal calculi. Epidemiology has significantly enhanced our comprehension and management of renal calculi. Such studies have measured alterations in disease patterns and the associated burden, while the identification of risk factors has transformed clinical practices and offered valuable insights into the pathophysiological mechanisms underlying calculi formation. Given the complexity of nephrolithiasis, a thorough understanding of its epidemiology, especially the interplay among various factors, may facilitate the development of strategies aimed at minimizing the risk of calculi formation. The examination of the urine composition of calculi offers insights into the pathogenesis and supplementary investigations to identify underlying conditions. Such analyses enable healthcare providers to develop tailored approaches aimed at reducing the likelihood of future calculi occurrences. At present, the information concerning the risk factors associated with nephrolithiasis is disjointed, and the connections among these factors are still unclear. Medicinal herbs have been employed for centuries due to their safety, efficacy, cultural acceptance, and reduced side effects compared to synthetic pharmaceuticals. This review critically assesses the potential efficacy of herbal remedies in the treatment of urolithiasis. The examination of the urine composition of calculi offers insights into the pathogenesis and supplementary investigations to identify underlying conditions. Such analyses enable healthcare providers to develop tailored approaches aimed at reducing the likelihood of future calculi occurrences. At present, the information concerning the risk factors associated with nephrolithiasis is disjointed, and the connections among these factors are still unclear. Medicinal herbs have been employed for centuries due to their safety, efficacy, cultural acceptance, and reduced side effects compared to synthetic pharmaceuticals. This review critically assesses the potential efficacy of herbal remedies in the treatment of urolithiasis.

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