NERIUM INDICUM: A COMPREHENSIVE REVIEW OF ITS MEDICINAL PROPERTIES AND PHARMACOLOGICAL ACTIVITIES

Renuka N. Sunagad*, Akash G. Wali, Kavita Nesur, Rani Bhadarakavathe

Nerium Indicum, also referred to as Indian oleander, is a revered medicinal herb with a wide range of therapeutic uses. It is a member of the Apocynaceae family and has been used extensively in Ayurveda, Siddha, and traditional medicine to treat conditions like cancer, microbial infections, inflammation, cardiovascular disease, and skin conditions. Its pharmacological potential is enhanced by the presence of cardiac glycosides, flavonoids, alkaloids, terpenoids, and saponins, according to phytochemical analyses. Numerous actions, such as cardiotonic, anti-inflammatory, antioxidant, antibacterial, analgesic, anticancer, hepatoprotective, and wound-healing properties, have been shown in contemporary pharmacological research. The plant's strong cardiotonic glycosides make it extremely dangerous despite its promising bioactivities, therefore it must be used carefully and at a consistent dosage.