EVALUATION OF PHYSICAL PARAMETERS OF LOCALLY MANUFACTURED AND IMPORTED DEXAMETHASONE 0.1% OPHTHALMIC DROPS IN KABUL CITY

Azimullah Wafa*, Rohullah Yousofazai, Ziarmal Teerzai, Roshaan Raihan, Najiburahman Rahmani, Mohiburahman Haleem

Background: Dexamethasone 0.1% ophthalmic drops are widely used for ocular therapy. Physical parameters like drop volume, pH, and packaging integrity are critical for safe use. Objective: To evaluate the physical characteristics of locally manufactured and imported Dexamethasone 0.1% ophthalmic drops available in Kabul. Methods: Seven brands were collected from local pharmacies. Dropper calibration, total volume, pH, and labeling were evaluated according to British Pharmacopoeia (2023) standards. Results: Most samples met pharmacopeia standards. Samples F6 failed volume criteria; samples F2, F4, F5, and F6 exceeded acceptable pH limits. Packaging deficiencies were noted in F1 and F3. Conclusion: While most drops were compliant, a few posed risks due to pH or volume deviations. Strict quality control is recommended.