World Journal of Pharmaceutical
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A Global Platform for Open Access, Peer-Reviewed, and Indexed Research in the
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ISSN: 2583-6579


Impact Factor: 5.111

ABSTRACT

COMPARATIVE STUDY OF MICROWAVE-INDUCED AND CONVENTIONAL SYNTHESIS OF SELECTED COMPOUNDS

Amruta Walvekar*, Dr. Rutuja Kamble

Microwave-assisted organic synthesis (MAOS) has emerged as a promising and efficient approach in modern organic chemistry. This technique offers a clean, simple, rapid, and economical alternative for the synthesis of a wide range of organic molecules. Conventional synthesis methods generally require prolonged heating, complex setups, and large amounts of solvents and reagents, which increase costs and contribute to environmental pollution. In contrast, microwave-assisted synthesis supports the principles of green chemistry by minimizing reaction time, energy consumption, and waste generation. In the present study, microwave-induced and conventional synthesis methods were compared for selected organic compounds. The microwave reactions were carried out using a microwave synthesizer, and the resulting products were purified according to literature-reported work-up procedures and recrystallized using appropriate solvents. Reaction progress was monitored periodically—at short intervals for microwave-assisted reactions and at hourly intervals for conventional methods. The comparative results demonstrated the efficiency, simplicity, and environmental advantages of microwave-assisted organic synthesis over traditional techniques.

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