PHYTOCHEMISTRY ANTI-UROLITHIATIC AND ANTIOXIDANT ACTIVITY OF ALSTONIA SCHOLARIS LINN R. BR.

Sd. Aliya Afra*, Dr. Shaik Salma, K. Venkata Swapna, V. Sai Muneeswari, Sd. Sheerin

Plants have served as the foundation for traditional healing practices across the globe for centuries and still offers new possibilities for treatments for various human ailments. In recent years, there has been a significant shift in perspective concerning the ethnopharmacological uses of phytochemical therapies. The present study investigates the phytochemical constitution and antioxidant activity of various solvent (aqueous, butanol and ethyl acetate) extracts of the leaf and bark of Alstonia scholaris. Alstonia scholaris is a member of the Apocynaceae family, which includes around 250 genera and 2000 species of tropical trees, shrubs, and vines. Nearly every part of this plant is utilized in medicinal practices, with the bark exhibiting antihelminthic and astringent properties. It has been employed in the treatment of chronic diarrhea, dysentery, and irregular bowel movements. The aim of the current study was to evaluate the phytochemical composition and determine the antioxidant activity of the solvent extracts derived from the bark and leaves of Alstonia scholaris. The leaves of Alstonia scholaris contain various phytochemical components. The qualitative phytochemical analysis reveals the presence of flavonoids, phenolic compounds, alkaloids, phenols, and tannins in the extracts of the leaves. The antibacterial and antioxidant properties of the leaf extracts from Alstonia scholaris were analysed. The TLC examination of the water extract from the bark, which exhibited the greatest antioxidant activity compared to the other extracts, was also conducted.