LIPID-BASED NANOPARTICLES: INNOVATIVE SOLUTIONS FOR EFFECTIVE DRUG DELIVERY

Sudhansu Sekhar Behera*, Pruthwiraj Dash, Raj Rajeswaree Tripathy, Jyotsna Rani Behera, Sagarika Prusti, Khipti Gayatri Mallick

Nanoparticles based on lipids appear to be an attractive approach in drug delivery to breach the area that exist in the way to efficiently deliver drugs, consequently they provide superior advantages in therapeutic delivery. The advantage of lipid-based nanostructures is that they are assembled using lipid-based materials which are biocompatible. Nanoparticles can carry heterologous drug molecules and enhance their solubility, stability and controlled release. The architecture provides the ability to traverse biological barriers and achieve targeted delivery with decreased toxicity to the human body. The efficiency of lipid-based nanoparticles in drug delivery control is achieved by various mechanisms including passive diffusion and stimuli-responsive release. In general, the use of lipid-based nanoparticles for drug delivery is a promising technology that can augment significantly the delivery of therapeutics into the clinics outperforming conventional formulations. Moreover, this approach will lead to safe and patient-friendly therapeutic interventions.