World Journal of Pharmaceutical
Science and Research

A Global Platform for Open Access, Peer-Reviewed, and Indexed Research in the
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ISSN: 2583-6579


Impact Factor: 5.111

ABSTRACT

PATTERNS AND IMPLICATIONS OF EXCESSIVE OPIOID PRESCRIPTION IN POSTOPERATIVE PATIENTS: A CROSS-SECTIONAL STUDY FROM A TERTIARY CARE CENTRE

Dollu Rakshitha*, Suhana Anjum

Background: Opioids are frequently prescribed for postoperative pain control. However, their excessive or inappropriate use can lead to serious complications such as dependence, overdose, and prolonged use. Recognizing the extent of overprescription and understanding its consequences are essential for enhancing postoperative care quality. Objective: This study aimed to evaluate the patterns of opioid prescribing among postoperative patients and to determine the prevalence and implications of overprescription. Methods: A cross-sectional observational study was conducted over six months at Tertiary care Hospital. A total of 150 postoperative patients were enrolled. Data on opioid type, dosage, duration, and adverse outcomes were collected. Patients were selected based on inclusion and exclusion criteria. Statistical analysis was performed using SPSS software, with significance set at p < 0.05. Results: A substantial proportion 62% of patients received opioids beyond the recommended duration, with tramadol and morphine being the most commonly prescribed. Notably, 24% of patients showed signs of opioid-related adverse effects, including nausea, constipation, dizziness, and early signs of dependency. Patients undergoing orthopedic and abdominal surgeries were more likely to be overprescribed opioids compared to other surgical groups. Conclusion: The findings highlight a critical gap in rational opioid use postoperatively. There is an urgent need for strict institutional guidelines, clinician education, and implementation of multimodal pain management strategies to prevent misuse and reduce potential harm.

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