A STUDY ON DUCHENNE MUSCULAR DYSTROPHY: CLINICAL FEATURES AND DISEASE PROGRESSION

Senthilraja M., Monika K.*, Suga Priya R., Priyadharshini K., Preetha S., Kumutha K.

Duchenne Muscular Dystrophy (DMD) is a genetic disorder characterized by progressive muscle weakness and degeneration, primarily affecting boys. It is caused by mutations in the dystrophin gene. DMD leads to loss of muscle function, respiratory and cardiac complications, and reduced life expectancy. It primarily affects boys and usually appears in early childhood. Symptoms include difficulty walking, frequent falls, and heart and respiratory problems. Although there is no cure, treatments such as corticosteroids, gene therapy, and physiotherapy can slow disease progression and improve quality of life. Current management focuses on slowing disease progression, managing symptoms, and improving quality of life. On-going research explores innovative treatments and potential cures.