EVALUATION OF ANTIOXIDANT AND ANTIMICROBIAL PROPERTY OF POLYHERBAL HYDROGEL

Dr. Ali Akbar K., Shada Sakkeer T.*, Muhdiya Sharin, Nejila, Aysha Ruby M., Hiba Sherin, Dr. S. V. Rekha, Dr. S. D. Shanmugakumar

The main objective of this study to evaluate the antimicrobial and antioxidant properties of a polyherbal hydrogel formulated using leaf extracts of Passiflora edulis Sims and Psidium guajava L. The plant extracts were incorporated into a hydrogel base and assessed for physicochemical characteristics, stability, and biological activity. Antimicrobial activity was evaluated against selected bacterial strains using standard in vitro methods, while antioxidant potential was determined through established free radical scavenging assays. The formulated polyherbal hydrogel exhibited significant antimicrobial activity against tested microorganisms and demonstrated notable antioxidant capacity, attributable to the presence of flavonoids, phenolic compounds, and other phytoconstituents in the extracts. The results suggest that the polyherbal hydrogel possesses promising antimicrobial and antioxidant properties and may serve as a potential topical therapeutic formulation for managing microbial infections and oxidative stress–related skin conditions.