IN VITRO ASSESSMENT OF ANTIOXIDANT ACTIVITY OF ETHANOLIC ROOT EXTRACT OF ABUTILON CRISPUM

Dr. R. Thiruvenkatasubramaniam*, T. Jothika, R. Kalamani, R. S. Kamalesh, S. Kamali, Dr. B. Sangameswaran

The present study was aimed to evaluate the in vitro antioxidant activity of ethanolic root extract of Abutilon crispum. The roots were collected, authenticated, shade dried, powdered and extracted using ethanol by maceration extraction method. Antioxidant activity was assessed using the DPPH radical scavenging assay. The extract exhibited concentration- dependent antioxidant activity. The IC50 value of the extract was found to be 352.88 µg/mL, indicating moderate antioxidant potential when compared to the standard ascorbic acid (IC50: 36.05 µg/mL). The activity may be attributed to the presence of bioactive phytoconstituents such as flavonoids and phenolic compounds. This study provides scientific evidence supporting the traditional use of Abutilon crispum managing oxidative stress.