AN OVERVIEW OF FAST DISOLVING TABLETS- A NEW ERA IN NDDS

Gopal Bharti*, Dr. Gaurav Bhaduka, Dr. Dilip Agrawal

Fast dissolving tablets emerge as one of the popular and widely accepted dosage forms, especially for paediatric patients because of incomplete development of the muscular and nervous system and a case of geriatric patients suffering from Parkinson’s disorder or hand tremors. Few solid dosage forms like capsules and tablets are present days facing the problems like difficulty in swallowing (dysphagia), resulting in many incidences of non-compliance and making the therapy ineffective. Oral dosage form and oral route are the most preferred route of administration for various drugs have limitations like first-pass metabolism, psychiatric patients, bedridden and uncooperative patients. FDTs are disintegrating or dissolve quickly in the saliva without a need of water. The oral route is the most preferred route of administration due to its low cost, ease of administration, and patient compliance. Pharmaceutical technologists introduced the novel dosage forms known as oral disintegrating tablet (ODT), fast disintegrating tablet (FDT), and mouth dissolving tablet (MDT). Recently researchers have developed fast dissolving tablet (FDT) which dissolve or disintegrate rapidly in mouth saliva without intake of water. This novel drug delivery such as FDT or MDT (mouth dissolving tablet) have overcome many disadvantages like dysphagia or non-accessibility of water while travelling. When compared with conventional dosage form FDT can be a useful alternative as well. This review article contains different techniques used for preparing FDT, silent features, various patented technologies, mechanism of super disintegration etc.