World Journal of Pharmaceutical
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ISSN: 2583-6579


Impact Factor: 6.916

ABSTRACT

FORMULATION AND EVALUATION OF HERBAL ANTI-ULCER CHURNA ENRICH VITAMIN B9

Kad Avishkar Suresh*, Dr. Sagar Eknath Tambe, Jadhav Jayesh Gangadhar, Jagnade Sujal Anil, Janawle Sahil Sonlal

Peptic ulcer is a common gastrointestinal disorder caused by excessive gastric acid secretion, stress, infection, and prolonged use of non-steroidal anti-inflammatory drugs (NSAIDs). Herbal medicines are widely used for the management of gastric ulcers due to their safety, natural origin, and fewer side effects compared to synthetic drugs. The present study aims to formulate and evaluate a polyherbal antiulcer churna enriched with natural Vitamin B9 using herbal ingredients such as Spinach, Tulsi, Aloe vera, and Glycyrrhiza glabra. Spinach was selected as a natural source of Vitamin B9 (folic acid), which helps in tissue repair and regeneration of gastric mucosa. Tulsi possesses antioxidant and anti-inflammatory properties, while Aloe vera provides soothing and ulcer-healing activity. Glycyrrhiza glabra is well known for its gastroprotective and mucosal protective effects. The prepared churna was evaluated for organoleptic properties, particle size, bulk density, angle of repose, moisture content, and antiulcer activity. The polyherbal formulation is expected to provide effective gastric protection, reduce ulcer symptoms, and promote healing naturally with minimal side effects. This study highlights the potential of herbal churna enriched with natural Vitamin B9 as a safe, economical, and effective approach for the management of peptic ulcer disease.

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