FORMULATION, EVALUATION AND ANTI-INFLAMMATORY ACTIVITY OF NYCTANTHES ARBOR TRISTS HERBAL GEL

A. Aruna*, M. Hemapriyadharshini, P. Jaishree, M. Jeevarani, M. Jeyaprakash, Dr. A. Babu Thandapani, Dr. S. Ramkumar

Extraction of crude extracts from the selected herbs followed by formulation and evaluation of herbal gel and lastly assessment of anti-inflammatory activity. Cold Maceration extraction method was employed for the extraction of Nyctanthes arbor-trist and menthol for the ratio of (1:5). Formulation of herbal gel by using Nyctanthes arbor-trist extract, HPMC, methyl paraben, propyl paraben and glycerin. The formulation was then evaluated by several tests like organoleptic character, pH determination, Homogenecity, Stability studies, Vicosity, Spreadability, Grittiness, Washability test and Skin irritation test. Further formulated gel was investigated for anti-inflammatory activity by using Egg albumin denaturation assay. Herbal gel was prepared and evaluated for various parameters and it showed anti-inflammatory activity also. This gel can be used for care and protection of skin.