ABSTRACT
AMA AND CHRONIC INFLAMMATION: BRIDGING AYURVEDIC CONCEPTS WITH MODERN PATHOPHYSIOLOGY
Dr. G. Vinay Mohan*, Dr. Girishkumar S. Dharmannavar, Dr. Prajakta Ransing
Ama is an Ayurvedic concept describing inadequately processed metabolic material produced by impaired Agni, contributing to channel obstruction and tissue dysfunction. It shares conceptual similarities with chronic inflammatory mechanisms such as metabolic endotoxemia, intestinal-barrier dysfunction, oxidative stress, and persistent immune activation, although it cannot be equated with any single biomarker. Ayurvedic management emphasizes restoring Agni and eliminating Ama through Langhana, Deepana, Pachana, Shodhana, and lifestyle modification. This review explores these conceptual links while emphasizing the need for validated assessment methods and rigorous clinical research.
[Full Text Article]