FORMULATION AND EVALUATION OF HERBAL TRANSDERMAL PATCH CONTAINING EXTRACT OF OCIMUM TENUIFLORUM

Aditi Khali, Nidhi Chaudhary*, Krati, Dr. Esha Vatsa, Dr. Amandeep Singh

The study on the formulation and evaluation of herbal transdermal patches containing Ocimum tenuiflorum extract highlights a significant advancement in the integration of natural remedies into modern drug delivery systems. Tulsi, a medicinal plant renowned for its anti-inflammatory, antimicrobial, and antioxidant properties, serves as the core therapeutic agent. In this study, a ethanolic extract of Tulsi leaves was prepared and incorporated the extract into a polymer matrix composed of suitable film forming agents such as HPMC and PVP along with plasticizers like glycerine or PEG to enhance flexibility and adhesion of the transdermal patch. The transdermal patches were developed using the solvent casting method and subjected to comprehensive physicochemical evaluations including thickness , weight variation , folding endurance , moisture content and weight uniformity .This study highlights the successful integration of a traditional herbal remedy into modern transdermal drug delivery system , paving the way for non-invasive, eco-friendly alternatives to conventional treatments which can be particularly beneficial for patients seeking holistic and sustainable approaches to health and wellness . The use of Tulsi in transdermal patches underscores its potential in enhancing holistic healthcare through innovative application. As a natural remedy with long history of use in traditional medicine Tulsi offers a promising avenue for developing novel therapeutic agents that are both effective and environmentally friendly